中国科技论文

2025, 12, v.20 1034-1046

乳腺癌术后继发淋巴水肿的临床评价方法及治疗研究进展

基金项目(Foundation): 国家自然科学基金面上项目（82272598）; 广东省医学科研基金项目（B2024008）; 深圳市大鹏新区医疗健康集团科研项目（DPJTKY202308）

邮箱(Email): 1147900529@qq.com;

DOI:

190	0	47
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摘要：

乳腺癌是全球女性发病率最高的恶性肿瘤之一。随着诊疗技术革新与规范化治疗推广，患者总体生存率显著提升、生存期大幅延长，但乳腺癌术后继发上肢淋巴水肿（breast cancer-related lymphedema, BCRL）作为常见且严重的慢性并发症，其发生率仍居高不下，不仅导致患肢功能障碍与形体改变，还显著降低患者生活质量，引发生理痛苦、心理压力及经济负担等多重问题。因此，对BCRL实施早期、精准且规范化的临床评估与有效干预，已成为乳腺癌全程管理体系及康复医学领域的核心研究课题。本文系统综述了BCRL的概念与流行病学特征，重点评析了当前临床常用及新兴的评价方法（涵盖主观症状评估、客观肢体测量、生物电阻抗法、影像学评估及生活质量评价等），并梳理了现阶段BCRL的治疗策略与研究前沿（包括综合消肿疗法（complex decongestive therapy, CDT）、手术治疗、药物治疗及新型康复技术等），旨在为临床工作者提供全面的诊疗参考思路，推动我国BCRL管理向规范化、精准化方向发展，最终改善患者预后。

关键词： 乳腺癌; 淋巴水肿; 临床评价; 康复; 综合消肿疗法; 综述;

Abstract：

Breast cancer ranks as one of the most common malignant tumors in women worldwide. Advances in diagnostic and therapeutic technology, along with the widespread adoption of standardized treatment protocols, have significantly improved overall survival rates and extended patient life expectancy. However, breast cancerrelated lymphedema(BCRL) remains a frequent and severe chronic complication following surgery, with persistently high incidence rates. BCRL not only leads to functional impairment and disfigurement of the affected limb but also markedly reduces patients' quality of life, causing physical pain, psychological stress, and imposing a substantial economic burden. Consequently, implementing early, accurate, and standardized clinical assessments along with effective interventions for BCRL has emerged as a central research priority within both the comprehensive breast cancer management framework and the field of rehabilitation medicine. This paper systematically reviews the definition and epidemiological characteristics of BCRL, critically evaluates current and emerging clinical assessment methods including subjective symptom evaluation, objective limb measurement, bioimpedance spectroscopy, imaging studies, and quality-of-life assessments, and summarizes current treatment strategies and research advancements, such as complex decongestive therapy(CDT), surgical options, pharmacological treatments, and novel rehabilitation technologies. The aim is to provide clinicians with comprehensive references for the diagnosis and management of BCRL, promote the standardization and precision of lymphedema care in China, and ultimately improve patient outcomes.

KeyWords： breast cancer; lymphedema; clinical evaluation; rehabilitation; complete decongestive therapy(CDT); review;

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参考文献

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基本信息:

中图分类号:R737.9

引用信息:

[1]江俊海,谢丽,司徒杏仙,等.乳腺癌术后继发淋巴水肿的临床评价方法及治疗研究进展[J].中国科技论文,2025,20(12):1034-1046.

基金信息:

国家自然科学基金面上项目（82272598）; 广东省医学科研基金项目（B2024008）; 深圳市大鹏新区医疗健康集团科研项目（DPJTKY202308）

发布时间：

2025-12-15

出版时间：

2025-12-15

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